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Table 1 Performance of the proposed method

From: Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information

 

Cross-validation

Independent test

Swiss-Prot1

MCC

0.607

0.604

0.42

Accuracy (%)

82.6

82.6

73.2

Sensitivity (%) (TP/(TP+FN))

94.9

94.7

84.0

True Positive Rate (%) (TP/(TP+FP))

81.6

81.6

75.0

  1. 1The proposed method was evaluated on SAPs from Swiss-Prot.