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Figure 4 | BMC Bioinformatics

Figure 4

From: Extending pathways based on gene lists using InterPro domain signatures

Figure 4

Sensitivity and specificity. Expected sensitivity (left) and specificity (right) of our method estimated through simulation of 100 sampled gene lists containing genes of varying numbers of KEGG pathways. 5 genes were sampled from each of 3, 5 or 10 different pathways, respectively, plus additional 50 random noise genes were added each time. The sensitivity and specificity was above 90% in all cases, the sampling variance indicated by the error bars is negligible.

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