Figure 5
From: Deducing topology of protein-protein interaction networks from experimentally measured sub-networks
Confidence score of core sub-network. a. Percentage of links in each bin of confidence score for the DPPI dataset [20] (red) and for several CSNs with distinct bait and prey scores in other colors (cyan, ≥ 0; orange, ≥ 0.25; green, ≥ 0.5; blue, ≥ 0.75; and magenta, = 1). In all cases, the CSNs have more links from higher bins of confidence, an independent estimation of the reliability of the data from the experimental setting. b. The average confidence score for the full DPPI network (upper panel) and the high confidence network (lower panel) for different CSNs defined by the same range of bait and prey score thresholds as in a (coloring same as in a). c. The percentage of the four-node motifs of the DPPI dataset (cyan) and of CSN (red) defined by bait and prey score ≥ 0.5.