Figure 1

Two-component mixture model for p -values with cutoff point y _c . This implies a decision rule with errors α ₁ and α ₂ . Further abbreviations: FP, false positives; TP, true positives; FN, false negatives; TN, true negatives. Note that here these quantities are all fractions (not counts) and that FP + TP + FN + TN = 1.