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Figure 5 | BMC Bioinformatics

Figure 5

From: Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis

Figure 5

Accuracy of MicroMerge v2 alignments for the 48 real data project markers, as compared to a manually obtained reference alignment for the lumped alignment format (a) and the one-to-one format (b). The manual alignment was obtained by eye (without the aid of a merging program) by using bin frequencies, relative base-pair size differences, and eight samples common to both data sets. Each plot shows the posterior probability of each marker plotted against its number of unique bins (summed from both data sets), where a black circle indicates agreement between the MicroMerge v2 alignment and its corresponding reference alignment and a white circle indicates disagreement. The horizontal line at 0.425 represents the same acceptance threshold for comparison between the methods. For the real data project the one-toone alignment format (b) is more accurate than the lumped alignment (a) because all correct MicroMerge v2 alignments had posterior probabilities above the threshold and only three markers were misaligned. In comparison the lumped format had four correctly aligned markers with posterior probabilities that fell below the threshold and eight markers total were misaligned.

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