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Table 4 MicroMerge v2 lumped alignment results for nine poorly aligned markers before and after remerging.

From: Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis

 

# Bins

Original

Re-merged

 

Marker

Lab1

Lab2

Pr(A o )

||A o - M o ||

Pr(A d )

||A d - M d ||

# Zeroed

D4S2961

6

9

0.248

0

0.958

0

3

D4S250

9

10

0.413

0

0.957

0

1

D4S2460

6

8

0.282

4

0.606

2

1

D4S1637

7

8

0.34

5

0.539

3

1

D4S3043

8

9

0.209

2

0.529

0

1

AFMA082Y

8

11

0.32

0

0.509

0

1

D4S2380

11

16

0.086

6

0.509

2

3

D4S3042*

13

16

0.192

6

0.386

3

8

D4S1560*

8

11

0.2

0

0.339

0

0

Average

 

8.92

0.25

2.83

0.61

1.17

1.67

Total

 

107

 

17

 

7

10

  1. A o is the original MicroMerge alignment, M o is its corresponding manually obtained alignment, A d is the re-merged Micromerge v2 alignment, and M d is its corresponding manually obtained alignment.
  2. *Posterior probability remained low after dropping problematic alleles and thus these markers' values were excluded from the 'Average' and 'Total' summaries.
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BMC Bioinformatics

ISSN: 1471-2105

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