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Table 1 Comparison of the discrimination capabilities of the naive stem kernels and the DAG-based stem kernels.

From: Directed acyclic graph kernels for structural RNA analysis

 

Naive stem kernels

DAG-based stem kernels

ncRNA type

ROC

SP

SN

Time (s)

ROC

SP

SN

Time (s)

tRNA

0.97

0.82

0.94

0.9

0.98

0.93

0.86

9.9 × 10-4

5S rRNA

0.97

0.97

0.74

5.1

1.00

1.00

0.95

2.2 × 10-3

miRNA

0.88

0.65

0.88

1.6

0.86

0.88

0.69

9.7 × 10-4

H/ACA snoRNA

0.80

0.80

0.54

12.8

0.89

0.90

0.72

4.1 × 10-3

C/D snoRNA

0.78

0.55

0.79

4.7

0.87

0.91

0.71

2.0 × 10-3

  1. The dataset contains five RNA families: tRNAs, miRNAs, 5S rRNAs, H/ACA snoRNAs, and C/D snoRNAs. ncRNA type: name of the target ncRNA family. ROC: ROC score, equal to the area under the ROC curve. SP: specificity of the discrimination of the target ncRNA family. SN: sensitivity of the discrimination of the target ncRNA family. Time: averaged time for each kernel computation on a 2.0 GHz AMD Opteron processor.