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Table 3 Non-coding RNA detection using SVDD in comparing the stem kernels with the local alignment kernels.

From: Directed acyclic graph kernels for structural RNA analysis

   

Stem kernels

Local alignment kernels

ncRNA type

Rfam Accession

N

ROC

SP

SN

nSV

ROC

SP

SN

nSV

5S ribosomal RNA

RF00001

449

1.000

1.000

0.940

27.8 (6.9)

1.000

1.000

0.886

48.4 (12.0)

U2 spliceosomal RNA

RF00004

566

0.997

0.999

0.912

51.8 (10.2)

0.999

1.000

0.844

92.0 (18.1)

tRNA

RF00005

495

0.983

0.948

0.939

26.8 (6.0)

0.999

0.999

0.853

67.0 (15.0)

Hammerhead ribozyme III

RF00008

588

1.000

0.998

0.971

14.2 (2.7)

1.000

1.000

0.968

19.3 (3.6)

U3 snoRNA

RF00012

471

1.000

1.000

0.915

36.3 (8.6)

0.959

1.000

0.775

95.5 (22.5)

U5 spliceosomal RNA

RF00020

510

0.999

0.998

0.939

30.3 (6.6)

1.000

1.000

0.882

57.2 (12.5)

tmRNA

RF00023

730

1.000

1.000

0.881

83.1 (12.6)

0.757

1.000

0.037

636.5 (96.9)

Group II intron

RF00029

604

0.996

0.989

0.942

30.9 (5.7)

0.999

1.000

0.922

48.7 (9.0)

mir-10

RF00104

620

1.000

1.000

0.977

13.3 (2.4)

1.000

1.000

0.984

10.7 (1.9)

U70 snoRNA

RF00156

608

0.998

0.996

0.952

25.5 (4.7)

1.000

1.000

0.951

29.0 (5.3)

RNAse P

-

656

0.998

1.000

0.887

66.2 (11.2)

0.629

1.000

0.006

587.5 (99.5)

SRP RNA

-

872

1.000

1.000

0.939

54.4 (6.9)

0.994

1.000

0.881

95.3 (12.1)

Total

 

7169

0.998

0.995

0.932

460.6 (7.1)

0.938

1.000

0.729

1787.1 (27.7)

  1. ncRNA type: name of the target ncRNA family. Rfam Accession: accession number of the target ncRNA family in Rfam. N: number of alignments. ROC: ROC score, equal to the area under the ROC curve. SP: specificity of the discrimination of the target ncRNA family. SN: sensitivity of the discrimination of the target ncRNA family. nSV: number of support vectors collected in the training processes and their rates against the numbers of the training alignments within parentheses.