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Table 3 Computational time comparison

From: NullHap – a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles

loci number of haplotypes observ. null alleles time for application
     Arlequin Phase HaploIHP NullHap
2 6 100 no 0.13 s 46 s 0.5 s 0.07 s
2 9 100 no 0.06 s 47 s 0.15 s 0.04 s
3 8 100 no 0.04 s 69 s 0.58 s 0.02 s
2 504 99 no 0.22 s 53 s - 37 s
2 540 99 no 0.34 s 58 s - 39 s
5 32 200 yes - - 14 s 0.78 s
7 128 200 yes - - 145 s 13 s
8 256 200 yes - - 450 s 61 s
9 512 200 yes - - 1300 s(8 s) 209 s
10 1024 200 yes - - 3 h (8 s) 2300 s
11 2048 200 yes - - 24 h (10 s) 3 h
15 32768 100 yes - - - 48 h
  1. Computational time for considered applications (HaploIHP in parenthesis with greedy algorithm). Results presented only for applications able to handle the given polymorphism, otherwise '-'.
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