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Table 4 The distribution of KIR haplotypes

From: NullHap – a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles

Haplo-type #

KIR 2

Psoriatis N = 116 (%)

Controls N = 123 (%)

OR

P value*

 

DS2

DL2/3

DS3/5

DL1

DS1

DS4/1D

    

1

null

3

null

1

1

1D

20 (17)

0

52.5

0.00018

2

1

2

3

null

1

1D

11 (9.6)

0

27

0.0058

3

null

3

3

null

null

1D

6 (5.3)

2 (1.5)

2.9

NS

4

null

3

5

1

1

null

6 (5.2)

7 (5.6)

0.9

NS

5

null

3

3

1

null

1D

15 (13)

30 (24)

0.5

NS

6

1

2

5

null

1

null

3 (2.5)

7 (6.4)

0.5

NS

7

null

3

null

1

null

1D

0

16 (13)

0.03

0.00018

8

1

2

-

null

1

1D

17 (15)

0

43.4

0.00018

9

null

3

-

1

1

1D

16 (14)

0

40.6

0.00018

10

null

3

-

1

1

DS4

6 (5.3)

0

14.5

NS

11

1

2

-

1

null

1D

7 (6)

3 (2.3)

2.4

NS

12

null

3

-

1

1

null

19 (16)

14 (11)

1.6

NS

13

null

3

-

null

null

1D

6 (5)

7 (5.7)

0.9

NS

14

null

3

-

1

null

1D

19 (16)

44 (36)

0.4

NS

15

1

2

-

null

null

DS4

3 (2.4)

8 (6.6)

0.4

NS

16

1

2

-

null

null

1D

0

7 (5.6)

0.07

NS

17

1

2

-

1

1

null

0

7 (5.6)

0.07

NS

18

null

3

-

1

null

DS4

0

7 (5.6)

0.07

NS

  1. *with Bonferroni correction (correction factor = 18)
  2. The distribution of KIR haplotypes among psoriasis patients and controls obtained with NullHap based on genotypes reported by Luszczek et al. [16]. Only haplotypes with frequency > 5% in either group are shown. Odds ratio (OR) calculated according to Haldane [22], P value calculated by Fisher exact test. NS -not significant.