TY - JOUR AU - Zhang, Feng AU - Liu, Jianfeng AU - Chen, Jie AU - Deng, Hong-Wen PY - 2008 DA - 2008/08/05 TI - HAPSIMU: a genetic simulation platform for population-based association studies JO - BMC Bioinformatics SP - 331 VL - 9 IS - 1 AB - Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical methods have been proposed to reduce the negative impact of population structure on PBAS. Due to lack of structural information in real populations, it is difficult to evaluate the impact of population structure on PBAS in real populations. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-9-331 DO - 10.1186/1471-2105-9-331 ID - Zhang2008 ER -