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Table 1 Parameters of linear models in MLDA for 16 cell lines in DMH dataset I

From: Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands

Unmethylation linear regression model
cell line intercetp (α) slope (β) σ R2 interceptds (α) slopeds (β) σ ds R2ds
A2780 -0.0003 1.0122 0.1727 0.9829 0.0005 1.0574 0.1897 0.978
A2780p3 -0.0003 1.0343 0.1212 0.9897 0.0018 1.1065 0.1425 0.9882
A2780p5 -0.0003 1.0138 0.1684 0.984 -0.0002 1.0728 0.1425 0.9883
A2780p6 0.0002 0.9914 0.1605 0.9778 -0.0001 1.0012 0.1638 0.9747
A2780p13 -0.0012 1.024 0.1628 0.9786 -0.0005 1.0744 0.1436 0.9852
A2780p14 -0.0022 1.0499 0.1523 0.9809 -0.0009 1.034 0.2069 0.9691
A2780cp70 0.0013 0.9604 0.2532 0.9524 -0.0002 1.0119 0.2402 0.9479
MCP1 0.0002 0.9946 0.145 0.9803 -0.0023 1.112 0.1452 0.9836
MCP2 0.0000 0.998 0.137 0.9727 -0.0028 1.0475 0.1719 0.9653
MCP3 0.0004 0.9932 0.2253 0.9183 -0.0023 1.0517 0.2795 0.8978
MCP4 0.0006 0.9838 0.1739 0.9718 -0.0028 1.077 0.1947 0.9751
MCP5 0.0009 0.9857 0.2464 0.9639 -0.0008 1.017 0.2166 0.9692
MCP6 -0.0022 1.0352 0.122 0.9751 -0.0068 1.1283 0.154 0.9752
MCP7 -0.0005 1.0079 0.1379 0.9791 -0.0045 1.1529 0.1588 0.9764
MCP8 -0.0028 1.0578 0.1903 0.9431 -0.0068 1.1193 0.1885 0.9575
MCP9 -0.0017 1.0331 0.1834 0.9614 -0.0091 1.1538 0.1691 0.9674
Methylation linear regression model
cell line intercetp (α) slope (β) σ R2 interceptds (α) slopeds (β) σ ds R2ds
A2780 -0.8839 0.8917 0.1491 0.9438 -0.8055 0.9086 0.1706 0.926
A2780p3 -1.1672 0.9797 0.1518 0.9553 -0.7414 0.9774 0.179 0.9438
A2780p5 -0.8991 0.8978 0.1515 0.9476 -0.9246 0.9766 0.1673 0.9523
A2780p6 -0.9455 0.9562 0.1838 0.9378 -1.1995 0.9641 0.1788 0.9324
A2780p13 -1.8918 0.9807 0.2535 0.8962 -1.8049 0.9652 0.2936 0.8512
A2780p14 -1.5637 0.9142 0.2549 0.8857 -1.4468 0.9066 0.2128 0.8837
A2780cp70 -1.0317 0.8501 0.1581 0.9115 -1.3074 0.8967 0.1541 0.9265
MCP1 -1.199 0.9781 0.1692 0.9467 -1.0935 1.0384 0.1775 0.9525
MCP2 -0.8037 0.9292 0.1486 0.9557 -0.9738 0.9381 0.2176 0.8848
MCP3 -1.1244 0.9151 0.1755 0.9482 -0.9303 0.9205 0.2599 0.8098
MCP4 -1.4326 0.9171 0.1418 0.966 -1.6205 0.961 0.2348 0.8323
MCP5 -1.1187 0.9425 0.1839 0.9404 -1.2007 0.9546 0.1757 0.9295
MCP6 -1.246 0.925 0.1966 0.9294 -1.2182 0.9826 0.2248 0.8989
MCP7 -1.8972 0.9909 0.1977 0.9442 -1.4894 1.0139 0.2458 0.8886
MCP8 -1.0219 0.9905 0.1975 0.9468 -0.4735 0.9421 0.228 0.8761
MCP9 -1.3399 0.9837 0.2073 0.9352 -1.1497 1.0078 0.1967 0.9115
  1. ds: dye swap
  2. σ: standard deviation
  3. R2: coefficient of determination