A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regulation of microtubule dynamics

Table 1 Growth rates of tau conditions (sample 1)

Condition	Manual	Automatic	Difference	Deviation	P-value
3R-1:20	3.99	4.19	0.20	4.93%	0.15
3R-1:38	3.58	3.76	0.18	4.80%	0.05
3R-1:45	2.02	2.27	0.25	12.58%	0.05
3R-1:55	2.02	2.28	0.26	12.68%	0.03
4R-1:20	4.71	4.56	0.15	3.33%	0.85
4R-1:38	3.96	4.19	0.23	5.86%	0.15
4R-1:45	3.51	3.65	0.14	4.14%	0.23
4R-1:55	2.59	2.84	0.25	9.45%	0.05
No-Tau	2.30	2.53	0.23	10.13%	0.27
Average			0.21	6.59%

The manual data is reproduced from Table III of (Levy et al., 2005) [19]. The third column shows growth rates (in μm/min) automatically computed from the manually tracked tips of the microtubules using an objective set of rules with no human interference. The relative ranks of the conditions remain the same.

ISSN: 1471-2105