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Figure 4 | BMC Bioinformatics

Figure 4

From: RNA STRAND: The RNA Secondary Structure and Statistical Analysis Database

Figure 4

Prediction accuracy achieved by various energy models. Sensitivity vs. positive predictive value (PPV) of various secondary structure prediction methods. Sensitivity is the number of correctly predicted base pairs divided by the number of base pairs in the reference structure, PPV is the number of correctly predicted base pairs, divided by the number of predicted base pairs. Higher prediction accuracy is achieved when the free energy parameters are obtained by training on a larger set of structures. The CONTRAfold prediction program uses a trade-off parameter γ between sensitivity and PPV, and thus we report predictions for γ ranging from 2 to 20.

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