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Table 1 Parameters for the model of the receptor trafficking network

From: SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool

Symbols of Parameters

Corresponding Biological Processes

k1

de novo synthesis of surface receptor

k2

formation of ligand-receptor complex

k3

dissociation of ligand-receptor complex

k4

recycling of internalized unbound receptor

k5

internalization of unbound surface receptor

k6

recycling of internalized ligand-receptor complex

k7

internalization of surface ligand-receptor complex

k8

dephosphorylation of ligand-receptor complex

k9

degradation of unbound receptor

k10

degradation of ligand-receptor complex