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Table 10 Comparison between our structural alphabet (used in SA-FAST) and those of Yang & Tung (used in 3D-BLAST) and de Brevern et al. (converted by PBE-T, a facility associated with PBE-align) for describing motifs found by MEME within the EGF family

From: Protein structure search and local structure characterization

  

Our SA

Yang & Tung's

de Brevern et al.'s

Sub-domain Type

A

B

C

A

B

C

A

B

C

EGF proteins

No.a

Hitsb

Covc

Hits

Cov

Hits

Cov

Hits

Cov

Hits

Cov

Hits

Cov

Hits

Cov

Hits

Cov

Hits

Cov

Type 1

24

23

95.8

22

91.7

23

95.8

11

45.8

21

87.5

19

79.2

18

75.0

14

58.3

18

75.0

Type 2

74

73

98.6

71

95.9

74

100.0

62

83.8

73

98.6

60

81.1

68

91.9

62

83.8

70

94.6

Type 3

117

116

99.1

106

90.6

61

52.1

54

46.2

102

87.2

25

21.4

109

93.2

112

95.7

48

41.0

Others

12

12

100.0

11

91.7

11

91.7

9

75.0

11

91.7

9

75.0

12

100.0

11

91.7

9

75.0

All

227

224

98.6

210

92.5

169

74.4

136

59.9

207

91.2

113

49.8

207

91.2

199

87.7

145

63.9

  1. aThe number of EGF proteins of a specific type, bA hit for a sub-domain occurred when more than half of the sub-domain residues were contained in a given motif. We present the number of hits of different types, cCov(Coverage) was defined as the ratio of the number of hits to the number of EGF proteins, e.g., if No. = 24 and Hits = 22, then Cov = 22/24 = 91.7%.