TY - JOUR AU - Mosca, Roberto AU - Brannetti, Barbara AU - Schneider, Thomas R. PY - 2008 DA - 2008/08/27 TI - Alignment of protein structures in the presence of domain motions JO - BMC Bioinformatics SP - 352 VL - 9 IS - 1 AB - Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under comparison are considered as rigid bodies. However, proteins are flexible entities often undergoing movements that alter the positions of domains or subdomains with respect to each other. Such movements can impede the identification of structural equivalences when rigid aligners are used. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-9-352 DO - 10.1186/1471-2105-9-352 ID - Mosca2008 ER -