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Figure 2 | BMC Bioinformatics

Figure 2

From: Identification and correction of abnormal, incomplete and mispredicted proteins in public databases

Figure 2

Error detected by MisPred routine for Conflict 1: the case of the Swiss-Prot entry C209C_MOUSE. The protein contains an extracellular C-type lectin domain but was found to lack both a signal peptide and transmembrane helices, whereas all closely related proteins (e.g. C209A_MOUSE, C209D_MOUSE [Swiss-Prot:Q91ZX1, Q91ZW8]) are type II transmembrane proteins. The sequence of this protein was corrected by targeted search of mouse genomic and EST sequences. The alignment shows the N-terminal parts of C209C_MOUSE, C209C_MOUSE_corrected, C209A_MOUSE and C209D_MOUSE. The predicted transmembrane helices of C209C_MOUSE_corrected, C209A_MOUSE and C209D_MOUSE are in red and underlined.

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