Figure 6
From: Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
Error detected by MisPred routine for Conflict 2. ENSXETP00000040601 of Xenopus tropicalis corresponds to the frog ortholog of Ephrin receptor A7, but lacks a typical transmembrane helix between its extracellular FN3 and cytoplasmic Pkinase domains. The mispredicted sequence was corrected by identifying the missing transmembrane sequence using frog EST sequences such as EL820950 [GenBank:EL820950]. The alignment shows the regions containing the transmembrane helices of Gallus gallus Ephrin receptor A7 [RefSeq:NP_990414], ENSXETP00000040601 and ENSXETP00000040601_corrected. The predicted transmembrane helices of NP_990414 and ENSXETP00000040601_corrected are in red and underlined, the mispredicted region of ENSXETP00000040601 is in italics.