Comparison results of the different tests based on simulation 1. The average ranks of the gene set related to the phenotype for Sub-GSE, GSEA, GSA, and SigPath for different percentages of correlated genes (PCG) and correlation coefficients within the chosen genes. The left panel compares the average ranks in 2-D plots in which each subplot corresponds to one value of PCG. For a given PCG, the average ranks from the four methods are plotted against the correlation coefficient between the correlated genes. The right panel shows the average rank versus the percentage of correlated genes and correlation coefficient in a 3-D plot.