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Table 5 Experimental results MPTOPO.

From: IgTM: An algorithm to predict transmembrane domains and topology in proteins

  

MPTOPO

  

Sn

Sp

CC

AC

Sov 3 obs

100%

≥ 90%

≥ 75%

igTM

exp5

0.651

0.708

0.443

0.439

0.491

0.312

0.400

0.509

 

exp6

0.672

0.752

0.511

0.469

0.576

0.409

0.472

0.572

TMHMM 2.0

0.634

0.882

0.663

0.563

0.666

0.121

0.240

0.465

Pred-TMR

0.572

0.893

0.617

0.542

0.630

0.061

0.145

0.345

Prodiv-TMHMM

0.609

0.887

0.643

0.547

0.647

0.087

0.199

0.410

HMMTOP

0.630

0.868

0.637

0.558

0.683

0.084

0.175

0.415

PHOBIUS

0.640

0.884

0.670

0.576

0.687

0.105

0.225

0.466

MEMSAT 3

0.667

0.821

0.581

0.584

0.701

0.139

0.283

0.506

TMpred

0.578

0.831

0.567

0.506

0.622

0.096

0.182

0.383

  1. Experimental results and comparison with results of other methods, with the MPTOPO α-helix database. As discussed in the Performance Measures section, 100%, ≥ 90% and ≥ 75% stand for segments correctly detected in that percentage.
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BMC Bioinformatics

ISSN: 1471-2105

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