Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast

Table 1 Classification of A-type and B-type ARSs based on local transcription patterns

Arrow represents direction of transcription. Filled circle represents location of ARS. (+) = transcriptional interference; (-) = no transcriptional interference. Using Fisher's exact with a test two-sided alternative, independence is rejected at 0.0018.

ISSN: 1471-2105