From: A Population Proportion approach for ranking differentially expressed genes
Parameter | Description | Remark |
---|---|---|
CTN | Ratio cutoff for inter-class ratios | Chosen based on the required magnitude of difference in expression between the two classes |
CTT, CNN | Ratio cutoff for intra-class ratios | Chosen based on allowable heterogeneity in expression within a class |
pcutoff | Significance value cutoff for significance of difference between the proportions of inter-class and intra-class populations greater than respective ratio cutoffs | Chosen based on required stringency in difference between the proportions of inter-class and intra-class populations greater than respective ratio cutoffs |