TY - JOUR AU - Melvin, Iain AU - Weston, Jason AU - Leslie, Christina S. AU - Noble, William S. PY - 2008 DA - 2008/09/22 TI - Combining classifiers for improved classification of proteins from sequence or structure JO - BMC Bioinformatics SP - 389 VL - 9 IS - 1 AB - Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there has been considerable interest in using discriminative learning algorithms, in particular support vector machines (SVMs), for classification of proteins. However, because sufficiently many positive examples are required to train such classifiers, all SVM-based methods are hampered by limited coverage. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-9-389 DO - 10.1186/1471-2105-9-389 ID - Melvin2008 ER -