miRNAminer: A tool for homologous microRNA gene search

BMC Bioinformatics

Table 2 Candidate non-registered miRNAs identified by miRNAminer in human.

Original information		Results in H. sapiens				RNA fold		Identity with original
miRNA	length (nt)	Chr	Position	Length (nt)	e-value	base pair %	ΔG	mature %	precursor %
mmu-mir-759	98	13	52282180	96	3.39E-048	72.9	-32	100	100
mmu-mir-763	120	12	64538060	120	4.99E-048	76.7	-57	95	95
mmu-mir-760	119	1	94084955	120	9.15E-048	66.7	-55	100	95
mmu-mir-708	109	11	78790709	109	1.66E-041	62.4	-50	100	94
mmu-mir-543	76	14	100568079	72	7.11E-027	61.1	-22	100	95
rno-mir-543	80	14	100568079	72	7.46E-027	61.1	-22	100	96
mmu-mir-670	100	11	43537789	89	7.67E-025	71.9	-36	100	91
mmu-mir-762	76	16	30812726	72	1.45E-024	77.8	-54	91	94
mmu-mir-764	108	X	113780174	96	3.83E-024	66.7	-42	95	91
mmu-mir-675	84	11	1974559	84	5.96E-022	71.4	-53	95	92
mmu-mir-711	82	3	48591339	74	1.24E-014	59.5	-31	91	88
mmu-mir-665	94	14	100411119	86	3.10E-014	65.1	-39	91	87
rno-mir-664	59	1	218440516	70	9.59E-012	60	-26	95	92
mmu-mir-322	95	X	133508324	91	2.72E-009	76.9	-47	95	85
rno-mir-322	95	X	133508327	87	2.72E-009	80.5	-45	95	85
mmu-mir-718	88	X	152938565	70	9.78E-009	71.4	-39	90	87
mmu-mir-709	88	3	186851919	71	1.21E-005	62	-27	100	70
mmu-mir-466	73	2	35362302	78	4.60E-005	61.5	-21	95	72
rno-mir-292	82	19	58982746	70	8.80E-004	65.7	-31	86	77
mmu-mir-669	97	17	69204319	71	1.33E-003	62	-22	90	86
mmu-mir-705	82	22	45887964	72	2.70E-003	58.3	-22	100	58
mmu-mir-207	79	17	73276373	70	4.10E-003	60	-25	96	62
mmu-mir-720	64	3	165541839	71	3.05E-002	59.2	-21	100	89
mmu-mir-761	76	1	110433694	71	4.76E-002	62	-31	81	84

The results are sorted according to e-values (based on BLAST search; [16]). Lengths refer to lengths of miRNA precursors. For each result, the table shows position, RNA fold quality and the identity ratio of the discovered miRNA candidates to the homolog in the original species. The existence of two occurrences for miR-322 and miR-543 (italicized) indicates that two origins (mouse and rat) of the same miRNA were found in Homo sapiens.

ISSN: 1471-2105