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Table 2 Sequence constraints learned by BBNet and GBNet in the five human YY1 clusters. The functional depth for each motif is in parentheses.

From: GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach

Cluster

BBNet

GBNet

 

Rules, P-value

Bayesian Score

Rules, P-value

Bayesian Score

H1

Presence of YY1 (0.02), 4.05E-12

-18.14

Distance between ETS (0.01) and YY1 (0.02):120 bp, 5.32E-13

-17.23

H2

Presence of YY1 (0.01), 5.43E-10

-22.64

Distance between WT1 (0.02) and YY1 (0.01):40 bp, 1.09E-10

-21.92

H3

Presence of YY1 (0.01), 3.94E-114

Presence of E2F (0.2), 1.54E-33

Presence of ELK1 (0.04), 1.13E-20

-161.70

Distance between YY1 (0.01) and E2F (0.01): 40 bp, 1.67E-121

Distance between ELK1 (0.04) and E2F (0.01): 220 bp, 7.64E-26

-151.71

H4

Presence of YY1 (0.03), 8.64E-6

-20.56

Distance between YY1 (0.01) and E2F1 (0.1): 520 bp, 8.82E-9

-17.71

H5

Presence of YY1 (0.02), 1.90E-6

-21.39

Distance between YY1 (0.02) and ELK1 (0.01):160 bp, 9.79E-8

-19.98