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Table 3 Comparison of the number of known complexes matched by the predicted clusters generated by IPCA and other previous algorithms

From: Modifying the DPClus algorithm for identifying protein complexes based on new topological structures

Overlapping Score Threshold

Algorithms

 

IPCA

DPClus(Ov)

CFinder

LCMA

MCODE

RNSC

STM

 

T in = 0.9

CP in = 0.5

k = 3

NA = 0.4

V WP = 0.1

K = 1200

No Merging

 

SP ≤ 2

D in = 0.9

  

Fluff = 0

  

OS ≥ 0.1

202

191

77

136

60

170

116

OS ≥ 0.2

165

128

54

105

35

115

57

OS ≥ 0.3

116

85

42

89

27

92

26

OS ≥ 0.4

104

74

33

74

24

71

18

OS ≥ 0.5

83

52

25

55

17

52

13

OS ≥ 0.6

67

41

19

45

13

26

10

OS ≥ 0.7

42

25

13

26

11

17

6

OS ≥ 0.8

36

20

7

20

8

11

5

OS ≥ 0.9

29

15

5

13

4

6

4

OS = 1.0

28

15

5

12

4

6

4