AGML Central web infrastructure. AGML XML format describing a 2-DE experiment is central to the AGML Central architecture. The web infrastructure is written in PHP programming language, a widely-used general-purpose scripting language, and the storage of the XML instance documents is provided by PostgreSQL, an open source object-relational database management system. The AGML document is stored as a logical unit within the database. This eliminates the need to store the document as blobs and also provides for fast retrieval of the data. Analysis software is written in MATLAB® (The MathWorks, Inc.), a technical computing environment ideal for handling high dimensional data.