Figure 9

Visual identification of potential errors in protein models using 'coloring' by MetaMQAP. The spectrum of colors from blue to red indicates the spectrum of residues predicted to be correct to incorrect. A) The crystal structure of the N-terminal GIY-YIG endonuclease domain of UvrC from Thermotoga maritima (PDB code 1ycz). B) A comparative model of the same protein based on an ideal alignment to a closely related structure of UvrC from Bacillus caldotenax (PDB code 1yd6). C) & D) Models with local 1 aa alignment shifts indicated by a white ellipse and predicted deviation from the native structure indicated by the shift of the color spectrum from blue towards yellow and red.