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Table 3 Comparison between 14 NBC and 20 heterogeneous lymphomas – top 16 genes selected by ABCR and AUC statistics

From: Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments

N Gene ID   Gene name ABCR AUC Group
1 GENE2495X + Unknown 0.5000 1.0000 Unknown
2 GENE1217X - NFkB2 0.5000 0.0000 4
3 GENE1602X - protein kinase (zpk) 0.5000 0.0000 5
4 GENE1191X - CREM 0.5000 0.0000 4
5 GENE1171X - Similar to spi-1 0.4964 0.0036 3
6 GENE1219X - IkB alpha 0.4964 0.0036 4
7 GENE3795X + AIM2 0.4964 0.9964 1
8 GENE1730X - Sgk 0.4929 0.0071 5
9 GENE1170X - CD83 0.4929 0.0071 1
10 GENE3702X + Unknown 0.4893 0.9893 Unknown
11 GENE2494X + Unknown 0.4857 0.9857 Unknown
12 GENE3280X + eIF-2B alpha subunit 0.4857 0.9857 4
13 GENE1160X - Unknown 0.4857 0.0143 Unknown
14 GENE589X - eIF-3 0.4821 0.0179 4
15 GENE1172X - CD83 0.4786 0.0214 1
16 GENE324X - Nak1 0.4786 0.0214 5
  1. Group 1: lymphocyte/macrophage related genes; Group 2: major histocompatibility complex related genes; Group 3: genes involved in malignant cell transformation; Group 4: genes related to nucleic acid metabolism or DNA transcription; Group 5: genes encoding various enzymes/kinases and other proteins. ABCR: Area between the ROC curve and the rising diagonal; AUC = Area under the ROC curve; "+" = overexpressed; "-" = underexpressed.