Table 5 Ovarian cancer-related TFs and their TRANSFAC entry IDs & descriptions
From: Knowledge-guided multi-scale independent component analysis for biomarker identification
Index | TF Name | PWM Access No. | Consensus Binding Site | Factor Description |
|---|---|---|---|---|
1 | AP-2 | M00189 | MKCCCSCNGGCG | Activator protein 2 |
2 | AP-2alpha | M00469 | GCCNNNRGS | Activating enhancer binding protein 2 alpha |
3 | AP-2alphaA | M01045 | ANNGCCTNAGGSNNT | Activating protein 2, AP-2A, Ker-1 |
4 | AP-2gamma | M00470 | GCCYNNGGS | Activator protein 2gamma, ERF-1 |
5 | AP-2rep | M00933 | CCCCGCCCCN | Specificity protein1, stimulating protein 1 |
6 | BRCA1 | M01082 | KTNNGTTG | Breast cancer type 1 susceptibility protein |
7 | E2F | M00516 | TTTSGCGCGMNR | EIIF protein, activator of myc, important for p107 promoter activity |
8 | Elk-1 | M00007 | NAAACMGGAAGTNCVH | Elk1, member of ETS oncogene family |
9 | NF-kappaB | M00774 | NNNNKGGRAANTCCCN | Nuclear factor kappa B, p50 |
10 | Sp1 | M00933 | CCCCGCCCCN | Specificity protein1, stimulating protein 1 |
11 | TGIF | M00418 | AGCTGTCANNA | 5'-TG-3' interacting factor, TG-interacting factor, TGFB-induced factor |
12 | c-Rel | M00053 | SGGRNTTTCC | Nuclear factor kappa B c-Rel, p68 |
13 | P53 | M00272 | NGRCWTGYCY | Tumor protein p53, TRP53 |
14 | ER | M00191 | NNARGNCANNNTGACCYNN | Estrogen receptor |