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Figure 1 | BMC Bioinformatics

Figure 1

From: A method for analyzing censored survival phenotype with gene expression data

Figure 1

Underlying direction revealed by censorSIR. The first projection direction identified by censor SIR for 22 gene expression profiles versus survival time. The left panel shows the projection weights on each of the 22 gene expression profiles, i.e., the eigenvector corresponding to the biggest eigenvalue. Notice we normalize the eigenvector β i so that β i Σ X β i MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGafqOSdiMbauaadaWgaaWcbaGaemyAaKgabeaakiabfo6atnaaBaaaleaacqWHybawaeqaaOGaeqOSdi2aaSbaaSqaaiabdMgaPbqabaaaaa@3532@ is equal to 1, i.e. V a r ( β i X ) = 1 MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaemOvayLaemyyaeMaemOCaiNaeiikaGIafqOSdiMbauaadaWgaaWcbaGaemyAaKgabeaakiabhIfayjabcMcaPiabg2da9iabigdaXaaa@37E5@ The right panel shows the scatter plot between projection direction and survival time.

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