Skip to main content

Table 4 Twenty-two genes selected by LA and correlations

From: A method for analyzing censored survival phenotype with gene expression data

Official Symbol Official Name Annotation
ABCG1 (3) ATP-binding cassette, sub-family G (WHITE), member 1 ATP binding; cholesterol homeostasis
BIRC5 (-0.31) baculoviral IAP repeat-containing 5 (survivin) Colorectal cancer; apoptosis
C5orf30 (3) chromosome 5 open reading frame 30  
CENPA (-0.32) centromere protein A chromosome organization and biogenesis
CTSL2 (-0.33) cathepsin L2 cathepsin L activity; proteolysis
E2F7 (-0.31) E2F transcription factor 7 breast cancer cell growth [30].
ERBB2 (3) v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases; Amplification and/or overexpression in numerous cancers, including breast and ovarian tumors
FAM150B (3) family with sequence similarity 150, member B  
H06509 (3) mRNA sequence  
HJURP (-0.31) Holliday junction recognition protein up-regulated in lung cancer
KIF20A (-0.30) kinesin family member 20A Collaboration of KIF20A and disc large homologue 5 is likely to be involved in pancre atic cancer [31]
KIFC1 (-0.30) kinesin family member C1 mitotic sister chromatid segregation
KRT6B (4) keratin 6B Cell Communication; ectoderm development
LOC284072 (3) hypothetical protein  
ORMDL2 (4) ORM1 (S. cerevisiae)-like 2 expressed in normal aorta
PDGFRA (4) platelet-derived growth factor receptor, alpha polypeptide Prostate cancer; cell proliferation
PELI1 (3) pellino homolog 1 (Drosophila) role in interleukin-1-mediated signaling through interaction with interleukin-1 receptor-associated kinase 4-IRAK-tumor necrosis factor receptor-associated factor 6 complex [32]
PERLD1 (5) per1-like domain containing 1 gastric cancer [33]
PRR11 (-0.32) proline rich 11 interact with E2F1, E2F4
PTTG2 (-0.33) pituitary tumor-transforming 2 chromosome organization and biogenesis
QSOX2 (-0.33) quiescin Q6 sulfhydryl oxidase 2 oxidoreductase activity; cell redox homeostasis
TROAP (-0.32) trophinin associated protein (tastin) cell adhesion
  1. The numbers in the parenthesis are either the number of times the gene appear in top/bottom 50 LA pairs or the correlation coefficient. Only genes with negative correlations are selected because positive correlations have smaller absolute value. The highest positive correlation is 0.2875, which is ranked as 31st by absolute values.