Table 4 Twenty-two genes selected by LA and correlations
From: A method for analyzing censored survival phenotype with gene expression data
Official Symbol | Official Name | Annotation |
|---|---|---|
ABCG1 (3) | ATP-binding cassette, sub-family G (WHITE), member 1 | ATP binding; cholesterol homeostasis |
BIRC5 (-0.31) | baculoviral IAP repeat-containing 5 (survivin) | Colorectal cancer; apoptosis |
C5orf30 (3) | chromosome 5 open reading frame 30 | Â |
CENPA (-0.32) | centromere protein A | chromosome organization and biogenesis |
CTSL2 (-0.33) | cathepsin L2 | cathepsin L activity; proteolysis |
E2F7 (-0.31) | E2F transcription factor 7 | breast cancer cell growth [30]. |
ERBB2 (3) | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 | member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases; Amplification and/or overexpression in numerous cancers, including breast and ovarian tumors |
FAM150B (3) | family with sequence similarity 150, member B | Â |
H06509 (3) | mRNA sequence | Â |
HJURP (-0.31) | Holliday junction recognition protein | up-regulated in lung cancer |
KIF20A (-0.30) | kinesin family member 20A | Collaboration of KIF20A and disc large homologue 5 is likely to be involved in pancre atic cancer [31] |
KIFC1 (-0.30) | kinesin family member C1 | mitotic sister chromatid segregation |
KRT6B (4) | keratin 6B | Cell Communication; ectoderm development |
LOC284072 (3) | hypothetical protein | Â |
ORMDL2 (4) | ORM1 (S. cerevisiae)-like 2 | expressed in normal aorta |
PDGFRA (4) | platelet-derived growth factor receptor, alpha polypeptide | Prostate cancer; cell proliferation |
PELI1 (3) | pellino homolog 1 (Drosophila) | role in interleukin-1-mediated signaling through interaction with interleukin-1 receptor-associated kinase 4-IRAK-tumor necrosis factor receptor-associated factor 6 complex [32] |
PERLD1 (5) | per1-like domain containing 1 | gastric cancer [33] |
PRR11 (-0.32) | proline rich 11 | interact with E2F1, E2F4 |
PTTG2 (-0.33) | pituitary tumor-transforming 2 | chromosome organization and biogenesis |
QSOX2 (-0.33) | quiescin Q6 sulfhydryl oxidase 2 | oxidoreductase activity; cell redox homeostasis |
TROAP (-0.32) | trophinin associated protein (tastin) | cell adhesion |