Skip to main content
Figure 4 | BMC Bioinformatics

Figure 4

From: Detection of the dominant direction of information flow and feedback links in densely interconnected regulatory networks

Figure 4

The number l of anti-hierarchical links vs the number of levels M in the annealing layout of the combined (a union of [10]and[9]datasets) protein phosphorylation network in human cell. The network consists of L = 2880 links and N = 1297 nodes (proteins). The nodes with zero in-degree and zero out-degree are always put on the top and bottom levels, correspondingly. The leftmost data point corresponds to the single intermediate level (3 levels total), the number of anti-hierarchical links clearly reaches its minimum of 59 links for M ≥ 18, which apparently is the length of the largest simple path in this network.

Back to article page