Discovery of dominant and dormant genes from expression data using a novel generalization of SNR for multi-class problems

Table 1 Details of the selected genes by the frequency-based method for the SRBCT data set

	Class	Image ID	Gene Symbol	Frequency	Ave. GDI	p-value	q-value
Dom	EWS	770394	FCGRT	100	1.88	0	0
		814260	FVT1	100	1.43	0	0
		377461	CAV1	99	1.46	0	0
		1435862	CD99	94	1.37	0	0
		866702	PTPN13	88	1.28	0	0
	BL	236282	WAS	100	2.19	0	0
		183337	HLA-DMA	67	1.82	0	0
		745019	EHD1	51	2.03	0	0
		1469292	PIM2	24	1.90	0	0
		47475	CYFIP2	24	1.85	0	0
	NB	812105	AF1Q	99	1.65	0	0
		134748	GCSH	64	1.45	0	0
		756401	RHEB	56	1.41	0	0
		325182	CDH2	33	1.38	0	0
		629896	MAP1B	32	1.32	0	0
	RMS	784224	FGFR4	100	1.60	0	0
		796258	SGCA	96	1.27	0	0
		244618	FNDC5	65	1.18	0	0
		839552	NCOA1	42	1.14	2.60E-06	0.0002
		769716	NF2	38	1.12	2.60E-06	0.0001
Dor	EWS	295985	CDK6	100	1.37	0	0
		448386	PBX3	73	0.96	5.11E-05	0.0011
		842820	PABPC4	43	0.78	0.0011	0.0115
		214572	CDK6	39	0.77	0.0003	0.0039
		366009	LYAR	24	0.93	0.0078	0.0457
	BL	204545	ANTXR1	70	2.04	0	0
		154472	FGFR1	68	2.15	0	0
		66552	C20orf194	57	2.12	0	0
		345538	CTSL	50	2.27	0	0
		142788	SERPINH1	21	2.04	0	0
	NB	810057	CSDA	85	1.29	0	0
		753418	VASP	62	1.16	1.73E-06	8.16E-05
		686164	DGKZ	42	1.13	6.07E-06	0.0002
		769716	NF2	34	1.12	9.53E-06	0.0003
		128126	CD55	33	1.47	0.0003	0.0038
	RMS	897177	PGAM1	73	0.75	0.0004	0.0053
		295986	EBP	61	0.80	0.0004	0.0053
		711959	POLR3C	41	0.72	0.0016	0.0150
		163174	TCEA1	31	0.76	0.0016	0.0148
		306921	EEF1E1	23	0.72	0.0028	0.0224

Using the training data, for each class the top five most frequently occurring genes are selected.

ISSN: 1471-2105