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Figure 1 | BMC Bioinformatics

Figure 1

From: Homology modelling of protein-protein complexes: a simple method and its possibilities and limitations

Figure 1

The relationship between sequence and structural similarity. 743 complexes from 40 interacting superfamily groups (ISGs) were analyzed. All pairs within each ISG were compared, for a total of 9630 pairwise comparisons. Small points correspond to comparisons involving at least one complex with either a small interface (buried area < 600 Ã…2) or a weak association energy (E int > -10 kcal/mol; see text). Points labelled A-G are discussed in the text. The horizontal line corresponds to Irmsd = 6 Ã…; the vertical line corresponds to a 35% sequence identity. Gray points correspond to comparisons where the MATRAS structural alignment provided fewer than 80% of the equivalent residues used for the Irmsd calculation. All the gray points lie below the 35% similarity threshold.

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