Figure 2From: Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfacesΔΔG models for Locked and Unlocked interfacial sidechains, Minimal-HighSA. Binding models fit to ΔΔGEXP, for Minimal-HighSA repacking. (a) ΔGSC-ROT calculated for Locked interfacial sidechains (R2 = 0.61). (b) ΔGSC-ROT calculated for Unlocked sidechains (R2 = 0.64).Back to article page