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Table 2 Weights for ASA-based binding models.

From: Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfaces

Model type

ΔG

ΔG

ΔG

ΔG

ΔΔG

ΔΔG

ΔG

ΔG

ΔΔG

ΔΔG

ΔG ROT-TRANS

0

10

0

10

-

-

0

0

-

-

Un/Locked

L

L

U

U

L

U

L

U

L

U

Packing Scheme

Minimal-HighSA

Complete-LowSA

ASA-NP

0.73

0.79

0.60

0.65

0.07

-0.04

0.58

0.56

-0.31

-0.23

ASA-P

-0.04

0.04

-0.08

0.02

-0.73

-0.67

-0.05

-0.11

-0.65

0.04

IONIS-FDDH

-0.01

-0.04

0.15

0.13

0.21

0.08

0.10

0.10

0.17

0.16

IONIS-DESOLV

0.15

0.09

0.06

0.01

1.29

0.97

0.20

0.19

0.67

0.61

SC-ROT

0.12

0.10

-0.22

-0.30

-0.02

-1.61

0.03

-0.02

-0.50

-0.61

R 2 correlation

0.69

0.64

0.61

0.58

0.61

0.64

0.69

0.68

0.54

0.55

Figure/Panel

1a

-

1d

-

2a

2b

6

-

-

-

  1. Weights are either w for ΔG models or w' for ΔΔG models. U/L is Unlocked/Locked interfacial sidechains, applied to SC-ROT.