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Table 1 List of ORFs containing C-, O- and N-Methyltransferase domains

From: In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites

Name of gene cluster ORF Accession no. CDD search Types of MT-domain Total
     C-MT O-MT N-MT  
     NRPS clusters   
Actinomycin acmC AAF42473 PF08242 - - 2 2
Anabaenopeptilide apdB CAC01604 PF08242 - - 2  
  apdE CAC01607 PF08241 - 1 - 3
Complestatin comC AAK81826 PF08242 - - 1 1
Cyclosporine simA CAA82227 PF08242 - - 7 7
Enniatin esyn1 CAA79245 PF08242 - - 1 1
Pristinamycin snbDE T30289 PF08242 - - 1 1
Pyochelin pchF AAD55801 PF08242 - - 1 1
Thaxtomin txtA AAG27087 PF08242 - - 1  
  txtB AAG27088 COG2226 - - 1 2
     PKS clusters   
Compactin mlcA BAC20564 PF08242 1 - -  
  mlcB BAC20566 PF08242 1 - - 2
Erythromycin eryG CAA42929 COG2226 - 1 - 1
Equisetin eqiS AAV66106 PF08242 1 - - 1
Fumonisin fum1 AAD43562 PF08242 1 - - 1
Lovastatin lovB Q9Y8A5 PF08242 1 - -  
  lovF AAD34559 PF08242 1 - - 2
Stigmatellin stiD CAD19088 PF08242 - 1 -  
  stiE CAD19089 PF08242 - 1 -  
  stiK CAD19094 PF01209 - 1 - 3
     Hybrid NRPS-PKS   
Bleomycin blmVIII AAG02357 PF08242 1 - - 1
Barbamide barF AAN32980 PF08242 - 1 -  
  barG AAN32981 PF08242 - - 1 2
Epothilone epoD AAF26922 PF08242 1 - - 1
Jamaicamide A jamJ AAS98781 PF08242 1 - -  
  jamN AAS98785 COG0500 - 1 - 2
Leinamycin lnmJ AAN85523 PF08242 1 - - 1
Melithiazol melE CAD89776 PF08242 - 1 -  
  melF CAD89777 PF08242 - 1 - 2
Microcystin mcyD BAB12210 PF08242 1 - -  
  mcyE BAB12211 - 1 - -  
  mcyG BAB12213 PF08242 1 - -  
  mcyA BAA83992 PF08242 - - 1 4
Myxothiazol mtaE AAF19813 PF08242 - 1 -  
  mtaF AAF19814 PF08242 - 1 - 2
Nodularin ndaC AAO64404 - 1 - -  
  ndaD AAO64405 PF08242 1 - -  
  ndaF AAO64407 - 1 - -  
  ndaA AAO64403 PF08242 - - 1  
  ndaE AAO64406 PF08242 - 1 - 5
Onnamide onnB AAV97870 PF08242 - 1 -  
  onnD AAV97872 PF08242 - 1 -  
  onnG AAV97875 PF08242 - 1 -  
  onnH AAV97876 COG2226 - 1 -  
  onnI AAV97877 PF08242 - 1 - 5
Pederin pedF AAS47564 PF08242 1 - -  
  pedA AAS47557 PF08241 - 1 -  
  pedE AAS47560 COG2226 - 1 - 3
Tubulysin tubF CAF05651 PF08242 1 - -  
  tubB CAF05647 PF08242 - - 1  
  tubC CAF05648 PF08242 - - 1 3
Yersiniabactin HMWP-1 AAC69588 PF08242 2 - - 2
Total     20 19 22 61
  1. List of ORFs containing methyltransferase domains in various experimentally characterized NRPS/PKS gene clusters. Table also lists the number and type of MT domains in each of the ORFs and results from PFAM analysis using CDD search.