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Table 2 Threading analysis of 18 representative MT containing sequences

From: In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites

Methyltransferases

Len.

2hg4

1qzz

1vl5

1vlm

1wzn

2gpy

2aot

1g6q

1xxl

1im8

2fr0

  

917

374

260

219

252

233

292

328

239

244

486

melit01_OM_001

609

C

-

C {100}

C

-

C

-

-

-

-

C

anaba01_OM_001

263

-

-

C {100}

C {100}

C

-

C

-

{100}

-

-

onnam04_OM_001

268

-

-

C {100}

C

C

-

-

-

{100}

-

-

peder01_OM_001

312

-

-

C {100}

C

-

-

-

-

{100}

-

-

stigm03_OM_001

256

-

-

C {100}

C {100}

C

-

-

-

{100}

-

-

eryth01_OM_001

306

-

-

C {100}

C

-

C

-

-

{100}

-

-

barba01_OM_001

422

-

-

C {100}

C

C

C

-

-

{100}

-

-

onnam01_OM_001

484

-

-

{100}

C {100}

-

-

C

-

{100}

{100}

-

bleom01_CM_001

640

C

-

C {100}

C {100}

C

C

-

-

{100}

{100}

C

nodul02_CM_001

720

-

C

C {100}

C {100}

-

C

C

-

{100}

-

C

compa01_CM_001

490

-

-

C {100}

C {100}

-

C

C

-

{100}

-

-

leina01_CM_001

432

-

C

C {100}

C {100}

C {100}

C

C

-

-

-

-

yersi01_CM_002

479

-

C

C

C

-

C

C

-

-

{95}

-

actin01_NM_001

422

-

-

{100}

{100}

C {100}

C

-

-

{100}

-

-

anaba01_NM_001

367

-

-

-

-

-

C

-

H {100}

-

-

-

cyclo01_NM_001

431

-

-

{100}

{100}

-

H

-

-

{100}

-

-

pyoch01_NM_001

390

-

H

{100}

C {100}

-

C

C

-

{100}

{100}

-

thaxt02_NM_001

362

-

-

{100}

C {100}

C

C

-

-

{100}

-

-

  1. Column 1 gives the unique name assigned to each MT containing sequence stretch, while the second column indicates their length. Column 3–13 lists the PDB IDs for the structures which show alignment with these sequences in fold recognition analysis using GenTHREADER and PHYRE servers. Results from GenTHREADER corresponding to confidence level CERTAIN and HIGH are labeled as C and H respectively. Similarly, PHYRE results corresponding to precision level 100% and 95% are labeled as 100 and 95 respectively in curly braces. (-) indicates the absence of that particular fold.