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Table 2 Threading analysis of 18 representative MT containing sequences

From: In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites

Methyltransferases Len. 2hg4 1qzz 1vl5 1vlm 1wzn 2gpy 2aot 1g6q 1xxl 1im8 2fr0
   917 374 260 219 252 233 292 328 239 244 486
melit01_OM_001 609 C - C {100} C - C - - - - C
anaba01_OM_001 263 - - C {100} C {100} C - C - {100} - -
onnam04_OM_001 268 - - C {100} C C - - - {100} - -
peder01_OM_001 312 - - C {100} C - - - - {100} - -
stigm03_OM_001 256 - - C {100} C {100} C - - - {100} - -
eryth01_OM_001 306 - - C {100} C - C - - {100} - -
barba01_OM_001 422 - - C {100} C C C - - {100} - -
onnam01_OM_001 484 - - {100} C {100} - - C - {100} {100} -
bleom01_CM_001 640 C - C {100} C {100} C C - - {100} {100} C
nodul02_CM_001 720 - C C {100} C {100} - C C - {100} - C
compa01_CM_001 490 - - C {100} C {100} - C C - {100} - -
leina01_CM_001 432 - C C {100} C {100} C {100} C C - - - -
yersi01_CM_002 479 - C C C - C C - - {95} -
actin01_NM_001 422 - - {100} {100} C {100} C - - {100} - -
anaba01_NM_001 367 - - - - - C - H {100} - - -
cyclo01_NM_001 431 - - {100} {100} - H - - {100} - -
pyoch01_NM_001 390 - H {100} C {100} - C C - {100} {100} -
thaxt02_NM_001 362 - - {100} C {100} C C - - {100} - -
  1. Column 1 gives the unique name assigned to each MT containing sequence stretch, while the second column indicates their length. Column 3–13 lists the PDB IDs for the structures which show alignment with these sequences in fold recognition analysis using GenTHREADER and PHYRE servers. Results from GenTHREADER corresponding to confidence level CERTAIN and HIGH are labeled as C and H respectively. Similarly, PHYRE results corresponding to precision level 100% and 95% are labeled as 100 and 95 respectively in curly braces. (-) indicates the absence of that particular fold.