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Table 2 Performance results of SVM_RFE and FW_SVM for lung cancer and normal tissue dataset

From: Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles

Method

N*

Sensitivity (%)

Specificity (%)

Accuracy (%)

Run Time

SVM_RFE

3.6

95.0

85.0

89.9

5.1 days

FW_SVM with PCA

2.6

89.1

94.3

91.7

8.7 minutes

FW_SVM with individual feature ranking

2.2

87.4

94.1

90.8

8.4 minutes

  1. *N: The average number of selected signature CpG sites.