Method | Metric | Description | Performance Rank | |
---|---|---|---|---|
 |  |  | Synth | Real # |
MI3 | 2*I(T;R1, R2)-I(T;R1)-I(T; R2) = I(T; R1|R2)+ I(T; R2|R1) | The sum of Correlative and Coordinative Criteria, which equals to the conditional mutual information between the target gene and the each regulator given the other regulator | 1 | 1 |
dMI3 | 2*I(T;R1, R2)-I(T;R1)-I(T; R2) | Discrete version of MI3, control score to show the strength of continuous mutual information | 3 | 2 |
Bayesian network (BN) | logP(T | R1, R2)†| Log conditional probability, control score which maximize correlation of the parent set to the target, while ignores the interaction between R1 and R2 | 2 | 3 |
Two-way MI (MI2) | I(T;R1)+I(T;R2) | Control two-way mutual information score to show the strength of three-way metric | 4 | 4 |