Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data

Table 1 Areas under ROC

Ontologies	Max.	Ave.	Tao	Wang	Schlicker
All (Root)	0.847	0.787	0.766	0.826	0.841
Biological Process	0.829	0.765	0.770	0.806	-
Molecular Function	0.722	0.715	0.717	0.718	-
Cellular Component	0.768	0.724	0.738	0.753	-

Areas under the curve (AUCs) are listed to provide detailed information on the PPI evaluation. Since the Schlicker method requires all three ontologies, it is only suitable in root ontology (ALL).

ISSN: 1471-2105