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Table 4 GO categories significantly enriched with "on" genes in infectious disease

From: Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classification

Biological Process

Cellular Component

Molecular Function

â–ª Immune response1, 2, 3, 4, 5

â–ª B cell receptor complex1, 2, 4, 5

â–ª Antigen binding1, 2, 4, 5

â–ª Humoral immune response by circulating immunoglobin1, 2, 4, 5

â–ª Immunoglobulin complex, circulating1, 2, 4, 5

â–ª Succinate dehydrogenase activity2,3,4

â–ª Positive regulation of B cell proliferation1, 2, 4, 5

â–ª Perinuclear region of cytoplasm1, 2, 4, 5

â–ª RNA binding3

â–ª Early endosome to late endosome transport1, 2, 4, 5

â–ª External side of plasma membrane1,4

â–ª Structural constituent of cytoskeleton3

â–ª Positive regulation of peptidyl-tyrosine phosphorylation1, 2, 4, 5

â–ª Membrane fraction4,5

â–ª Protein binding3

â–ª B cell receptor signaling pathway1, 2, 4, 5

â–ª Cytoplasm3,5

â–ª Electron-transferring-flavoprotein

â–ª Activation of MAPK activity1, 2, 4

â–ª Cytoskeleton3

â–ª dehydrogenase activity5

â–ª tRNA aminoacylation for protein translation1,4

â–ª Actin cytoskeleton3

â–ª Endopeptidase inhibitor activity5

â–ª Antigen processing and Presentation1,4

â–ª Extracellular region5

â–ª Structural molecule activity5

â–ª DNA methylation3

â–ª Proteinaceous extracellular matrix5

â–ª Extracellular matrix structural constituent5

â–ª Translational initiation3

â–ª Collagen5

 

â–ª Negative regulation of protein kinase activity3

  

â–ª Defense response3

  

â–ª Inflammatory response4

  

â–ª Hemocyte development4

  

â–ª Cell-cell adhesion4

  

â–ª Pyridine nucleotide biosynthetic process4

  

â–ª Respiratory burst4

  

â–ª Response to calcium ion3,4

  

â–ª Tricarboxylic acid cycle5

  

â–ª Cell adhesion5

  

â–ª Blood coagulation5

  

â–ª Sensory perception of sound3,5

  
  1. P-values < = 0.001 indicate significance in malaria, influenza A, hepatitis C-PBMCs and hepatitis C-Liver. P-values < = 0.01 indicate significance in HIV. 1malaria, 2influenza A, 3HIV, 4hepatitis C-PBMC, 5hepatitis C-liver