|
J48
|
Naïve Bayes
|
SMO
|
---|
a) Sequences folding to the top 10% and the bottom 10% of designable conformations for the hexagon
|
96.8% correct
|
95.8% correct
|
98.3% correct
|
|
AUC .97
|
AUC 0.99
|
AUC 0.98
|
|
Sens: 1.0
|
Sens: 1.0
|
Sens: 0.997
|
|
Spec: 0.94
|
Spec: 0.92
|
Spec: 0.97
|
b) Sequences folding to the top 10% and the bottom 10% of designable conformations for the triangle
|
92.7% correct
|
82.4% correct
|
95.0% correct
|
|
AUC 0.93
|
AUC 0.92
|
AUC 0.95
|
|
Sens: 0.93
|
Sens: 0.76
|
Sens: 0.92
|
|
Spec: 0.92
|
Spec: 0.86
|
Spec: 0.97
|
- a We compare random subsets of sequences corresponding to the top 10% and the bottom 10% of designable structures for the a) hexagon, and b) triangle. Prediction accuracy and area under the curve (AUC), sensitivity (Sens) and specificity (Spec) for each method are given.