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Figure 2 | BMC Bioinformatics

Figure 2

From: Identifying differential correlation in gene/pathway combinations

Figure 2

Distribution of gene-pathway correlation loss, prostate data. Distribution of loss of correlation between normal and tumor samples (ie, signed SGPC) in the prostate data set (red) and 6 permutation resamplings (black) of all pairs. While not exhaustive, the few resamplings show a much narrower distribution centered around zero; none of the resampled pairs exhibited values exceding S = 0.9. By contrast, the observed distribution is wider, and biased towards loss of correlation in tumor samples with respect to normal samples.

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