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Figure 1 | BMC Bioinformatics

Figure 1

From: Natural computation meta-heuristics for the in silico optimization of microbial strains

Figure 1

The process of solution decoding and evaluation. The solutions (individuals) are encoded using the proposed set-based representation where the genes to be deleted are represented. Each individual is decoded by imposing additional constraints to the original metabolic model. FBA is the method used to simulate the cellular behaviour that will be associated to a given fitness, related with the productivity in a given interesting compound.

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