Figure 5
Comparison between functional distance and sequence similarity for pairs of Yeast proteins annotated with TAS and IDA evidence codes. The alignments covers most of the range of sequence similarities, whose distribution is shown in panel D. (A) Hausdorff distance (calculated using our functional metric) vs. sequence identity. The mean and the deviation values for each interval are also shown. (B) Hausdorff distance calculated using Lord's Semantic Similarity vs. sequence identity. (C) Mean values for both distance metrics. (D) Distribution of the percentage of Yeast protein pairs in each sequence similarity category.