Skip to main content
Figure 8 | BMC Bioinformatics

Figure 8

From: Defining functional distances over Gene Ontology

Figure 8

The whole spectra of the P matrix [λ i (P)]iUis analyzed selecting the first K eigenvalues and for each selection obtaining a partition of the MF-GO terms C K . In panel A, the values of the gap measure calculated for C K are represented and according to the Spectral Clustering theory, the best partition C* minimizes the gap value. The red circle encloses the eigenvalues of the spectra that generate 'good' clusterings (interval [4, 93]). Panel B shows the result of applying a second criterion to select the best number of groups from the interval. The correlation coefficient of the ordered similarity matrix with an ideal block diagonal matrix is calculated for each partition. The best clustering is obtained by selecting the first 93 eigenvalues.

Back to article page