Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method

Table 1 Mean relative angle changes of the gene pairs sharing and not sharing GO terms¹⁾

GO terms²⁾	Angle before	Mean relative angle change (mean ± SEM)	p-value³⁾	% angle change⁴⁾
Shared	0 – 0.3 π	-0.00400 π ± 0.00028 π	8.2 × 10^-8	-25.0%
	0.7 – 1 π	0.00435 π ± 0.00032 π	1.5 × 10^-7	27.2%
Not shared	0 – 0.3 π	0.00328 π ± 0.00022 π	4.9 × 10^-8	20.5%
	0.7 – 1 π	-0.00257 π ± 0.00015 π	1.7 × 10^-8	-16.0%

¹⁾ A summary of the results from 10 sets of 80,000 randomly selected gene pairs. ²⁾ GO biological process and cellular compartment terms; see Fig. 5 for the exact rules for shared and not shared. ³⁾ The probability of the mean relative angle change being zero or having the opposite sign by one-sample, one-sided t-test. ⁴⁾ The ratio in percents of the mean of the mean relative angle changes of the selected gene pairs to the mean of the absolute values of the relative angle changes of all the sampled gene pairs.

ISSN: 1471-2105